SARS-CoV-2 MagIC Beads

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Reproducible, fast, reliable

An elegant simple workflow for SARS-COV-2 viral RNA enrichment:

SARS-CoV-2 viral RNA enrichment with Magnetic Instant Capture Beads (MagIC Beads) is the best option for:

• Extraction for detection – Research Use Only.
• Pulldown and analysis of SARS-CoV-2 viral RNA.
• Large scale isolation from cell lysates.
• Epigenetic modification studies.
• Targeted RNA sequencing with NGS and 3rd Generation Sequencing such as Nanopore.

Protocols:

• Isolation from swab samples using SARS-CoV-2 Extraction MagIC Beads
• Isolation from saliva using SARS-CoV-2 Extraction MagIC Beads
• Viral RNA enrichment using RNA Seq MagIC Beads SARS-CoV-2

Unmatched enrichment levels:

Directly from unprocessed RNA:

MagIC Beads for RNA enrichment provide the first standardized solution for the capture of any RNA of interest from complex samples of unprocessed RNA. Whether for targeted sequencing or for any other downstream application the unique properties of MagIC Beads RNA enrichment kits offer exceptional value. MagIC Beads for RNA enrichment are particularly useful for those experiments that can be benefited by bringing the resolution of the sequencing to a group of transcripts or a single transcript.

The ability of MagIC Beads to capture full length RNA targets makes them especially attractive when used in combination with sequencing technologies capable of producing long reads. This is particularly pronounced in the case of direct RNA sequencing with Oxford Nanopore sequencing, where the relatively low number of reads produced by the platform makes the transcriptome wide applications challenging. 

Capture up to 99% of the target sequence from the input sample:

The kits consist of the target-specific MagIC Beads and sets of optimized buffers. They feature standardized capture conditions and capture probes properties, which ensure uniformly high efficiency of the system on varying RNA targets, independently of their length or secondary structures. The beads provide very high target enrichment levels, at the same time being able to capture up to 99% of the target sequence from a sample.

Efficiency guaranteed by design:

For any custom target transcript the optimal number of probes is established based on the target length and nucleotide composition. Experimentally validated design approach is used to provide uniformly highly efficient capture probe arrays for any target. Every probe is extensively screened against potential binding to any off-targets in the transcriptome of interest to ensure superb probe specificity. 

Additional information:

‣ Supplied with beads, and hybridization and wash buffers.
‣ 1 reaction (SARS-CoV-2 Extraction MagIC Beads) = 7,5 pmol of capture probes.
‣ 1 reaction (RNA Seq MagIC Beads SARS-CoV-2) = 20 pmol of capture probes.
‣ Shipping condition: room temperature.
‣ Storage Temperature: 4°C.
‣ Durability: 36 months from the date of manufacture.

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